Data Sheet

MSDS

JNJ-54717793 [CAS 1628843-99-1]

CAS No:	1628843-99-1
Applications:	Neuroscience-Neuromodulation
MW:	458.41
Formula:	C₂₂H₁₈F₄N₆O
SMILES:	O=C(C1=C(C2=NC=CC=N2)C(F)=CC=C1)N3[C@H](CC[C@@H]43)C[C@H]4NC5=CN=C(C(F)(F)F)C=N5
Purity:	98.85
Description:	JNJ-54717793, as a brain penetrant, is an orally active, selective and high affinity orexin-1 receptor (OX1R) antagonist (plasma EC50=85 ng/mL). The Ki values of JNJ-54717793 for hOX1R (human OX1R) and hOX2R are 16 nM and 700 nM, respectively. JNJ-54717793 is a potent compound of anxiety disorders[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only