m-PEG4-Br [CAS 110429-45-3]
Partner: MedChemexpress LLC
CAS No: | 110429-45-3 |
Applications: | Cancer-programmed cell death |
MW: | 271.15 |
Formula: | C9H19BrO4 |
SMILES: | COCCOCCOCCOCCBr |
Purity: | 97.83 |
Description: | m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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