Torin 2 [CAS 1223001-51-1]
Partner: MedChemexpress LLC
CAS No: | 1223001-51-1 |
Applications: | Cancer-Kinase/protease |
MW: | 432.40 |
Formula: | C24H15F3N4O |
SMILES: | O=C1N(C2=C(C=C1)C=NC3=CC=C(C=C32)C4=CC=C(N=C4)N)C5=CC=CC(C(F)(F)F)=C5 |
Purity: | 99.98 |
Description: | Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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