CL2A-SN-38 [CAS 1279680-68-0]
Partner: MedChemexpress LLC
| CAS No: | 1279680-68-0 |
| Applications: | Cancer-programmed cell death |
| MW: | 1480.61 |
| Formula: | C73H97N11O22 |
| SMILES: | O=C(O[C@](C1=C(CO2)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C1)=O)(CC)C2=O)OCC6=CC=C(NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7N=NC(CNC(C8CCC(CN9C(C=CC9=O)=O)CC8)=O)=C7)=O)=O)=O)C=C6 |
| Purity: | 99.07 |
| Description: | CL2A-SN-38 is a agent-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody agent conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A-SN-38 uses hydrolyzable linker to deliver active agents within tumor cells and in the tumor microenvironment, resulting in bystander effects[1]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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