Data Sheet

MSDS

Mitapivat [CAS 1260075-17-9]

CAS No:	1260075-17-9
Applications:	Cancer-Kinase/protease
MW:	450.55
Formula:	C₂₄H₂₆N₄O₃S
SMILES:	O=S(C1=C2N=CC=CC2=CC=C1)(NC3=CC=C(C(N4CCN(CC5CC5)CC4)=O)C=C3)=O
Purity:	99.97
Description:	Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[1][2][3].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only