Data Sheet

MSDS

MS31 [CAS 2366264-12-0]

CAS No:	2366264-12-0
Applications:	Cancer-programmed cell death
MW:	341.45
Formula:	C₂₀H₂₇N₃O₂
SMILES:	NCC1=CC(CN)=C(OC)C(OCCCN2CC(C=CC=C3)=C3C2)=C1
Description:	MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 potently inhibits binding of trimethyllysine-containing peptides to SPIN1. MS31 is not toxic to nontumorigenic cells[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only