ML375 [CAS 1488362-55-5]
Partner: MedChemexpress LLC
CAS No: | 1488362-55-5 |
Applications: | Neuroscience-Neuromodulation |
MW: | 424.83 |
Formula: | C23H15ClF2N2O2 |
SMILES: | O=C1N2[C@@](N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C=C4)C5=C1C=CC=C5 |
Purity: | 99.0 |
Description: | ML375 (VU0483253) is a potent, highly selective, brain-penetrant and orally active M5 mAChR negative allosteric modulator (NAM) with IC50s of 300 nM and 790 nM for human and rat M5, respectively. ML375 is inactive at human and rat M1-M4[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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