Data Sheet

MSDS

MPT0E028 [CAS 1338320-94-7]

CAS No:	1338320-94-7
Applications:	Cancer-Kinase/protease
MW:	344.38
Formula:	C₁₇H₁₆N₂O₄S
SMILES:	O=C(/C=C/C1=CC2=C(C=C1)N(CC2)S(=O)(C3=CC=CC=C3)=O)NO
Purity:	99.63
Description:	MPT0E028 is an orally active and selective HDAC inhibitor with IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively[1]. MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity[2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only