20(S)-Hydroxycholesterol [CAS 516-72-3]
Partner: MedChemexpress LLC
CAS No: | 516-72-3 |
Applications: | Cancer-programmed cell death |
MW: | 402.65 |
Formula: | C27H46O2 |
SMILES: | C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1 |
Purity: | 98.70 |
Description: | 20(S)-hydroxyCholesterol (20?-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 ?M in a gene transcription reporter assay using NIH3T3 cells[1][2]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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