PF-04802367 [CAS 1962178-27-3]
Partner: MedChemexpress LLC
| CAS No: | 1962178-27-3 |
| Applications: | Neuroscience-Neurodegeneration |
| MW: | 361.78 |
| Formula: | C16H16ClN5O3 |
| SMILES: | O=C(C1=C(C2=CC=C(OC)C(Cl)=C2)OC=N1)NCCCN3N=CN=C3 |
| Purity: | 98.84 |
| Description: | PF-04802367 (PF-367) is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3? enzyme assay and 1.1 nM based on ADP-Glo assay.�PF-04802367 shows desirable central nervous system (CNS)�properties and potency. PF-04802367 is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3? and GSK-3?) with IC50�values of 10.0 and 9.0 nM in mobility shift assays, respectively[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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