Data Sheet

MSDS

AOH1160 [CAS 2089314-57-6]

CAS No:	2089314-57-6
Applications:	Cancer-programmed cell death
MW:	396.44
Formula:	C₂₅H₂₀N₂O₃
SMILES:	O=C(C1=C2C=CC=CC2=CC=C1)NCC(NC3=CC=CC=C3OC4=CC=CC=C4)=O
Purity:	99.30
Description:	AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen (PCNA) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis. AOH1160 selectively kills many types of cancer cells (mean GI50=330 nM) without causing significant toxicity to a broad range of nonmalignant cells[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only