Simvastatin acid (ammonium) [CAS 139893-43-9]
Partner: MedChemexpress LLC
CAS No: | 139893-43-9 |
Applications: | Neuroscience-Neuromodulation |
MW: | 453.61 |
Formula: | C25H43NO6 |
SMILES: | O=C(C[C@@H](C[C@@H](CC[C@H]1[C@H](C=CC2=C[C@@H](C[C@@H]([C@]12[H])OC(C(C)(CC)C)=O)C)C)O)O)[O-].[NH4+] |
Purity: | 99.32 |
Description: | Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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