MAZ51 [CAS 163655-37-6]
Partner: MedChemexpress LLC
| CAS No: | 163655-37-6 |
| Applications: | Cancer-Kinase/protease |
| MW: | 314.38 |
| Formula: | C21H18N2O |
| SMILES: | CN(C1=C2C=CC=CC2=C(C=C1)/C=C3C(NC4=C/3C=CC=C4)=O)C |
| Purity: | 98.61 |
| Description: | MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. MAZ51 inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. MAZ51 had no effect on ligand-induced autophosphorylation of EGFR, IGF-1R and PDGFR?. MAZ51 blocks proliferation and induces apoptosis in a wide variety of tumor cells. Antitumor activity[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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