SPR inhibitor 3 [CAS 1292285-54-1]
Partner: MedChemexpress LLC
| CAS No: | 1292285-54-1 |
| Applications: | COVID-19-immunoregulation |
| MW: | 262.30 |
| Formula: | C14H18N2O3 |
| SMILES: | O=C(NCCC1=C(C)NC2=C1C=C(O)C=C2)COC |
| Purity: | 99.84 |
| Description: | SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 ?M). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels[1][2][3]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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