Description: | 11-Beta-hydroxyandrostenedione (4-Androsten-11?-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11?-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11?-hydroxysteroid dehydrogenase (11?HSD) isozymes inhibitor. As 4-androstenedione increases, measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism[1][2]. |