TP0463518 [CAS 1558021-37-6]
Partner: MedChemexpress LLC
| CAS No: | 1558021-37-6 |
| Applications: | Metabolism-sugar/lipid metabolism |
| MW: | 431.83 |
| Formula: | C20H18ClN3O6 |
| SMILES: | ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2 |
| Purity: | 98.62 |
| Description: | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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