CGP 78608 (hydrochloride) [CAS 1135278-54-4]
Partner: MedChemexpress LLC
CAS No: | 1135278-54-4 |
Applications: | Neuroscience-Neurodegeneration |
MW: | 414.58 |
Formula: | C11H14BrClN3O5P |
SMILES: | OP(O)([C@H](NCC1=CC(Br)=CC(NC2=O)=C1NC2=O)C)=O.[H]Cl |
Description: | CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity[1][2]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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