BIO5192 (hydrate) [CAS ] (10mM in DMSO)
Partner: MedChemexpress LLC
| Applications: | COVID-19-immunoregulation |
| MW: | 826.79 |
| Formula: | C38H46Cl2N6O8S.1/2H2O |
| SMILES: | O=[S](N(CCC1)[C@@H]1C(N[C@H](C(O)=O)CCNC([C@H](CC(C)C)N(C)C(CC(C=C2)=CC=C2NC(NC(C=CC=C3)=C3C)=O)=O)=O)=O)(C4=CC(Cl)=CC(Cl)=C4)=O.O.[1/2] |
| Purity: | 99.78 |
| Description: | BIO5192 hydrate is a selective and potent integrin ?4?1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to ?4?1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels[1][2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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