JNJ10191584 (maleate) [CAS 869497-75-6]
Partner: MedChemexpress LLC
| CAS No: | 869497-75-6 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 394.81 |
| Formula: | C17H19ClN4O5 |
| SMILES: | OC(/C=C\C(O)=O)=O.O=C(N1CCN(CC1)C)C2=NC3=CC(Cl)=CC=C3N2 |
| Description: | JNJ10191584 (VUF6002) maleate (compound 40) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 maleate shows 540-fold selectivity to H4 receptor over the H3 receptor with a Ki value of 14.1 ?M. JNJ10191584 maleate inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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