Data Sheet

MSDS

Roxindole (hydrochloride) [CAS 108050-82-4]

CAS No:	108050-82-4
Applications:	Neuroscience-Neuromodulation
MW:	382.93
Formula:	C₂₃H₂₇ClN₂O
SMILES:	OC1=CC2=C(C=C1)NC=C2CCCCN3CCC(C4=CC=CC=C4)=CC3.[H]Cl
Purity:	99.53
Description:	Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only