Data Sheet

MSDS

Valproic acid (sodium) [CAS 1069-66-5]

CAS No:	1069-66-5
Applications:	Cancer-Kinase/protease
MW:	166.19
Formula:	C₈H₁₅NaO₂
SMILES:	O=C(O[Na])C(CCC)CCC
Purity:	98.14
Description:	Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 ?M), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only