Data Sheet

MSDS

Valproic acid [CAS 99-66-1]

CAS No:	99-66-1
Applications:	Cancer-Kinase/protease
MW:	144.21
Formula:	C₈H₁₆O₂
SMILES:	CCCC(CCC)C(O)=O
Purity:	98.67
Description:	Valproic acid (VPA) is an orally active HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 ?M), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches[1][2][3][4][5][6][7].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only