Data Sheet

MSDS

Ki20227 [CAS 623142-96-1] (10mM in DMSO)

CAS No:	623142-96-1
Applications:	COVID-19-immunoregulation
MW:	480.54
Formula:	C₂₄H₂₄N₄O₅S
SMILES:	O=C(NC1=CC=C(C=C1OC)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC(C)C4=NC=CS4
Purity:	99.30
Description:	Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFR? (platelet-derived growth factor receptor ?). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction[1].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only