Data Sheet

MSDS

A-841720 [CAS 869802-58-4]

CAS No:	869802-58-4
Applications:	Neuroscience-Neuromodulation
MW:	343.45
Formula:	C₁₇H₂₁N₅OS
SMILES:	O=C1C2=C(C3=C(N(C)C)C=CN=C3S2)N=CN1N4CCCCCC4
Description:	A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only