Data Sheet

MSDS

SCH442416 [CAS 316173-57-6]

CAS No:	316173-57-6
Applications:	Neuroscience-Neuromodulation
MW:	389.41
Formula:	C₂₀H₁₉N₇O₂
SMILES:	NC1=NC(N(CCCC2=CC=C(OC)C=C2)N=C3)=C3C4=NC(C5=CC=CO5)=NN14
Purity:	99.68
Description:	SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only