ICA-069673 [CAS 582323-16-8]
Partner: MedChemexpress LLC
| CAS No: | 582323-16-8 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 269.63 |
| Formula: | C11H6ClF2N3O |
| SMILES: | O=C(NC1=CN=C(Cl)N=C1)C2=CC=C(F)C(F)=C2 |
| Purity: | 99.65 |
| Description: | ICA-069673 is a KCNQ2/Q3 potassium channel activator. ICA-069673 demonstrates greater selectivity for KV7.2/7.3 over KV7.3/KV7.5, with EC50s of 0.69 ?M and 14.3 ?M, respectively. ICA-069673 inhibits spontaneous phasic and nerve-evoked contractions in guinea pig detrusor smooth muscle (DSM). ICA-069673 also decreases the global intracellular Ca(2+) concentration in DSM cells[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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