Applications: | Functional, FC, IF, IHC(p), IP, WB |
Isotype: | Mouse |
Purification: | PBS, 0.1% BSA, 0.05% azide |
Conjugation: | CF405S |
Description: | Recognizes a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO) (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.Primary antibodies are available purified, or with a selection of fluorescent CF� Dyes and other labels. CF� Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF�405S and CF�405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
Further Information: | Functional studies (published)|Flow, surface (verified)|IF (verified)|IHC, FFPE (verified)|IP (published)|WB (published) |
Shipping Conditions: | Ship at ambient |
Storage: | Store at 4 C |
Usage: | Research Use Only |