Applications: | Enzyme Activity, SDS-PAGE |
Species Reactivity: | Rat |
MW: | 14.3kDa (128aa);;13.5-18KDa (SDS-PAGE under reducing conditions.) |
Purity: | > 95% by SDS - PAGE |
Description: | CST3, also known as cystain-C, is secreted type 2 cysteine proteinase inhibitors of the cystatin superfamily. It is involved in processes such as tumor invasion and metastasis, inflammation and some neurological diseases. It inhibits many cysteine proteases such as papain and cathepsins B, H, K, L and S. Recombinant rat CST3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Further Information: | Sequence: GTSRPPPRLL GAPQEADASE EGVQRALDFA VSEYNKGSND AYHSRAIQVV RARKQLVAGI NYYLDVEMGR TTCTKSQTNL TNCPFHDQPH LMRKALCSFQ IYSVPWKGTH TLTKSSCKNA LEHHHHHH |
Synonym: | Cystain-C, CST3, CYSC |
Ascension Number: | P14841 |
NCBI EntrezGene: | NP_036969 |
Shipping Conditions: | Ship on cold packs |
Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage: | Research use only |