Applications: | SDS-PAGE |
Species Reactivity: | Mouse |
MW: | 30.3kDa (263aa) confirmed by MALDI-TOF |
Purity: | > 90% by SDS - PAGE |
Description: | Apoa1 also known as Apolipoprotein A-I, is the major protein component of high density lipoprotein (HDL) in plasma. This protein promotes cholesterol efflux from tissues to the liver for excretion. And it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apoa1 are associated with HDL deficiency including Tangier disease. Recombinant mouse Apoa1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques |
Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSDEPQSQW DKVKDFANVY VDAVKDSGRD YVSQFESSSL GQQLNLNLLE NWDTLGSTVS QLQERLGPLT RDFWDNLEKE TDWVRQEMNK DLEEVKQKVQ PYLDEFQKKW KEDVELYRQK VAPLGAELQE SARQKLQELQ GRLSPVAEEF RDRMRTHVDS LRTQLAPHSE QMRESLAQRL AELKSNPTLN EYHTRAKTHL KTLGEKARPA LEDLRHSLMP MLETLKTQVQ SVIDKASETL TAQ |
Synonym: | Apolipoprotein A-I, Alp-1, apo-AI, Apoa-1, apoA-I, Brp-14,Ltw-1, Lvtw-1, Sep-1, Sep-2, Sep2, Apolipoprotein AI |
Ascension Number: | Q00623 |
NCBI EntrezGene: | NP_033822 |
Shipping Conditions: | Ship on cold packs |
Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage: | Research use only |