| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Mouse |
| MW: | 14.9 kDa (138aa) |
| Purity: | > 90% by SDS - PAGE |
| Description: | Growth/differentiation factor 15, also known as GDF15, is a member of the TGF superfamily. It has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. Recombinant mouse GDF15 fused to His-tag at N-terminus, was expressed in E. coli. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSSAHAHPR DSCPLGPGRC CHLETVQATL EDLGWSDWVL SPRQLQLSMC VGECPHLYRS ANTHAQIKAR LHGLQPDKVP APCCVPSSYT PVVLMHRTDS GVSLQTYDDL VARGCHCA |
| Synonym: | Growth/differentiation factor 15 precursor, Growth/differentiation factor 15 precursor, MIC-1, NAG-1, SBF |
| Ascension Number: | Q9Z0J7 |
| NCBI EntrezGene: | NP_035949 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
