| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Human |
| MW: | 17.6kDa (159aa) |
| Purity: | > 85% by SDS - PAGE |
| Description: | TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. TNFSF13 and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Recombinant human TNFSF13 protein, fused to T7-tag at N-terminus, was expressed in E. coli. |
| Further Information: | Sequence: MASMTGGQQM GRGSHMAVLT QKQKKQHSVL HLVPINATSK DDSDVTEVMW QPALRRGRGL QAQGYGVRIQ DAGVYLLYSQ VLFQDVTFTM GQVVSREGQG RQETLFRCIR SMPSHPDRAY NSCYSAGVFH LHQGDILSVI IPRARAKLNL SPHGTFLGL |
| Synonym: | tumor necrosis factor (ligand) superfamily member 13, tumor necrosis factor (ligand) superfamily, member 13, APRIL, CD256, TALL2, TRDL-1, ligand, uNQ383/PRO715 |
| Ascension Number: | O75888 |
| NCBI EntrezGene: | NP_742085 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
