| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 11.8 kDa (102aa), confirmed by MALDI-TOF. |
| Purity: | > 95% by SDS - PAGE |
| Description: | AHSP (Alpha-hemoglobin stabilizing protein), also known as ERAF (Erythroid associated factor), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of alpha-hemoglobin during normal erythroid cell development. It specifically protects free alpha-hemoglobin from precipitation in live cells and in solution. This protein is downregulated in transmissible spongiform encephalopathies (TSEs). It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. Recombinant AHSP protein was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MALLKANKDL ISAGLKEFSV LLNQQVFNDP LVSEEDMVTV VEDWMNFYIN YYRQQVTGEP QERDKALQEL RQELNTLANP FLAKYRDFLK SHELPSHPPP SS |
| Synonym: | Alpha-hemoglobin stabilizing protein, ERAF, EDRF, Alpha-hemoglobin stabilizing protein Alpha hemoglobin stabilizing protein, Erythroid associated factor, Erythroid differentiation associated factor, Erythroid differentiation related factor, |
| Ascension Number: | Q9NZD4 |
| NCBI EntrezGene: | NP_057717 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
