Applications: | WB |
Species Reactivity: | Human |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | The protein encoded by this gene is a member of theregulator of G protein signaling (RGS) family. RGS family membersshare similarity with S. cerevisiae SST2 and C. elegans egl-10proteins, which contain a characteristic conserved RGS domain. RGSproteins accelerate GTPase activity of G protein alpha-subunits,thereby driving G protein into their inactive GDP-bound form, thusnegatively regulating G protein signaling. RGS proteins have beenimplicated in the fine tuning of a variety of cellular events inresponse to G protein-coupled receptor activation. The biologicalfunction of this gene, however, is unknown. Two transcript variantsencoding the same isoform exist. |
Further Information: | This RGS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human RGS13. |
Synonym: | Regulator of G-protein signaling 13, RGS13, RGS13 |
Ascension Number: | O14921 |
NCBI EntrezGene: | 6003 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |