| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 40S subunit. The protein belongsto the S19E family of ribosomal proteins. It is located in thecytoplasm. Mutations in this gene cause Diamond-Blackfan anemia(DBA), a constitutional erythroblastopenia characterized by absentor decreased erythroid precursors, in a subset of patients. Thissuggests a possible extra-ribosomal function for this gene inerythropoietic differentiation and proliferation, in addition toits ribosomal function. Higher expression levels of this gene insome primary colon carcinomas compared to matched normal colontissues has been observed. As is typical for genes encodingribosomal proteins, there are multiple processed pseudogenes ofthis gene dispersed through the genome. |
| Further Information: | This RPS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-133 amino acids from the C-terminal region of human RPS19. |
| Synonym: | 40S ribosomal protein S19, RPS19 |
| Ascension Number: | P39019 |
| NCBI EntrezGene: | 6223 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
