| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | The protein encoded by this gene is a DNA-bindingtranscription factor and is a member of the NR1 subfamily ofnuclear hormone receptors. The specific functions of this proteinare not known; however, studies of a similar gene in mice haveshown that this gene may be essential for lymphoid organogenesisand may play an important regulatory role in thymopoiesis. Inaddition, studies in mice suggest that the protein encoded by thisgene may inhibit the expression of Fas ligand and IL2. Twotranscript variants encoding different isoforms have been found forthis gene. |
| Further Information: | This RORC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human RORC. |
| Synonym: | Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3, RAR-related orphan receptor C, Retinoid-related orphan receptor-gamma, RORC, NR1F3, RORG, RZRG |
| Ascension Number: | P51449 |
| NCBI EntrezGene: | 6097 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
