| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene is one of two genes which encode a proteinsimilar to the Drosophila protein dachshund, a transcription factorinvolved in cell fate determination in the eye, limb and genitaldisc of the fly. The encoded protein contains two characteristicdachshund domains: an N-terminal domain responsible for DNA bindingand a C-terminal domain responsible for protein-proteininteractions. This gene is located on the X chromosome and issubject to inactivation by DNA methylation. The encoded protein maybe involved in regulation of organogenesis and myogenesis, and mayplay a role in premature ovarian failure. Multiple transcriptvariants encoding different isoforms have been found for this gene. |
| Further Information: | This DACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human DACH2. |
| Synonym: | Dachshund homolog 2, Dach2, DACH2 |
| Ascension Number: | Q96NX9 |
| NCBI EntrezGene: | 117154 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
