| Applications: | FC, IHC-P, WB |
| Species Reactivity: | Human, Mouse |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | Pre-mRNA splicing is catalyzed by the spliceosome.U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5'splice site and branch-point sequence. U11 and U12 snRNPs arecomponents of U12-type spliceosome and function as a molecularbridge connecting both ends of the intron. The protein encoded bythis gene contains a RNA recognition motif. It was identified asone of the protein components of U11/U12 snRNPs. This protein andmany other U11/U12 snRNP proteins are highly conserved in organismsknown to contain U12-type introns. These proteins have been shownto be essential for cell viability, suggesting the key roles inU12-type splicing. |
| Further Information: | This ZCRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the C-terminal region of human ZCRB1. |
| Synonym: | Zinc finger CCHC-type and RNA-binding motif-containing protein 1, U11/U12 small nuclear ribonucleoprotein 31 kDa protein, U11/U12 snRNP 31 kDa protein, U11/U12-31K, ZCRB1 |
| Ascension Number: | Q8TBF4 |
| NCBI EntrezGene: | 85437 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
