Ordering Details
Cat Number:	AP11960c-ev
Size:	80uL
Price:	£117.00
Quantity:
Shipping:	£12.00

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Data Sheet

MSDS

XRCC5 [Center K439] [RB17385], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:	WB, FC, IF
Species Reactivity:	Human
Isotype:	Rabbit Ig
Purification:	Affinity Purified Rabbit Polyclonal Antibody
Description:	The protein encoded by this gene is the 80-kilodaltonsubunit of the Ku heterodimer protein which is also known asATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku isthe DNA-binding component of the DNA-dependent protein kinase, andit functions together with the DNA ligase IV-XRCC4 complex in therepair of DNA double-strand break by non-homologous end joining andthe completion of V(D)J recombination events. This genefunctionally complements Chinese hamster xrs-6, a mutant defectivein DNA double-strand break repair and in ability to undergo V(D)Jrecombination. A rare microsatellite polymorphism in this gene isassociated with cancer in patients of varying radiosensitivity.
Further Information:	This XRCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-450 amino acids from the Central region of human XRCC5.
Synonym:	X-ray repair cross-complementing protein 5, 364-, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku80, Ku86, Lupus Ku autoantigen protein p86, Nuclear factor IV, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), XRCC5, G22P2
Ascension Number:	P13010
NCBI EntrezGene:	7520
Shipping Conditions:	Ship on cold packs
Storage:	Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:	Research use only

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Confocal immunofluorescent analysis of XRCC5 Antibody (Center K439)(Cat#AP11960c) with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).