| Applications: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Isotype: | IgG1 |
| Purification: | Mouse Monoclonal Antibody |
| Description: | Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.Isoform Bcl-X(S) promotes apoptosis. |
| Further Information: | Purified His-tagged BCL2L1 protein was used to produced this monoclonal antibody. |
| Synonym: | Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1, BCL2L, BCLX |
| Ascension Number: | Q07817 |
| NCBI EntrezGene: | 598 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
