| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | IgM |
| Purification: | Mouse Monoclonal Antibody |
| Description: | This gene encodes the human homolog of the proto-oncogenec-kit. C-kit was first identified as the cellular homolog of thefeline sarcoma viral oncogene v-kit. This protein is a type 3transmembrane receptor for MGF (mast cell growth factor, also knownas stem cell factor). Mutations in this gene are associated withgastrointestinal stromal tumors, mast cell disease, acutemyelogenous lukemia, and piebaldism. Multiple transcript variantsencoding different isoforms have been found for this gene. |
| Further Information: | Purified His-tagged KIT protein(Fragment) was used to produced this monoclonal antibody. |
| Synonym: | Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR |
| Ascension Number: | P10721 |
| NCBI EntrezGene: | 3815 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
