TeMu terkib [CAS 1951483-29-6] (10mM in DMSO)
Partner: MedChemexpress LLC
| CAS No: | 1951483-29-6 |
| Applications: | Cancer-Kinase/protease |
| MW: | 453.56 |
| Formula: | C22H27N7O2S |
| SMILES: | O=C(C(C=C(C1=NC(NC2=CC=NN2C)=NC=C1)S3)=C3C4(C)C)N4CCN5CCOCC5 |
| Purity: | 99.88 |
| Description: | Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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