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Cat Number:AP22029c-ev
Size:50uL
Price:£117.00
Quantity:
Shipping:£12.00

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Data Sheet
MSDS

 

ACO1 [Centre] [RB54996], Rabbit Polyclonal Antibody

Partner: Abcepta, Inc.

Applications:WB
Species Reactivity:Human, Mouse, Rat
Isotype:Rabbit Ig
Purification:Purified Rabbit Polyclonal Antibody
Description: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
Further Information:This ACO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 354-388 amino acids from the Central region of human ACO1.
Synonym:Cytoplasmic aconitate hydratase, Aconitase, 4.2.1.3, Citrate hydro-lyase, Ferritin repressor protein, Iron regulatory protein 1, IRP1, Iron-responsive element-binding protein 1, IRE-BP 1, ACO1, IREB1
Ascension Number:P21399
NCBI EntrezGene:48
Shipping Conditions:Ship on cold packs
Storage:Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles.
Usage:Research use only

 

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All lanes : Anti-ACO1 Antibody (Center) at 1:2000 dilutionLane 1: human kidney lysateLane 2: human liver lysateLane 3: U-2OS whole cell lysateLane 4: A431 whole cell lysateLane 5: mouse kidney lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG,  (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 98 kDaBlocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-ACO1 Antibody (Center) at 1:2000 dilutionLane 1: human kidney lysateLane 2: human liver lysateLane 3: U-2OS whole cell lysateLane 4: A431 whole cell lysateLane 5: mouse kidney lysateLysates/proteins at 20 �g per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 98 kDaBlocking/Dilution buffer: 5% NFDM/TBST.