Your Basket 0

 

Ordering Details

Cat Number:ATGA0126-50ul
Size:50ul
Concentration:1mg/ml
Price:£118.00
Quantity:
Shipping:£10.00

Document Links

Data Sheet
MSDS

 

CBR3 [AT7E8], Mouse Monoclonal Antibody

Partner: ATGen

Applications:ELISA, WB, ICC/IF
Species Reactivity:Human
Isotype:Mouse IgG1 kappa
Immunogen:Recombinant human CBR3 (1-277aa) purified from E. coli
Purification:By protein-G affinity chromatography
Conjugation:Unconjugated
Description:Carbonyl reductase 3 (CBR3) is one of several monomeric NADPH-dependent oxidoreductases. This protein catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It also contains three exons spanning 11. 2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. Some studies suggest that it mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy.
Further Information:The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Synonym:Carbonyl reductase 3, CBR3, NADPH-dependent carbonyl reductase, Carbonyl reductase (NADPH) 3, EC 1.1.1.184, hCBR3, Carbonyl reductase (NADPH) 3 EC 1.1.1.184, NADPH dependent carbonyl reductase 3, SDR21C2, Short chain dehydrogenase/reductase family 21C member 2.
Ascension Number:O75828
NCBI EntrezGene:NP_001227
Shipping Conditions:Ship on cold packs
Storage:Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage:Research use only

 

Insight Biotechnology Ltd reserves the right to change pricing without notice

 

The lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CBR3 antibody (1:1000).

The lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CBR3 antibody (1:1000).

ICC/IF analysis of CBR3 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human   CBR3 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

ICC/IF analysis of CBR3 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CBR3 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).